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*The above table shows the key highlights of the table and provides Table of Contents for this report. This report provides you the license. Therefore,you cannot use this report with any license. *Highlights: *Table of Contents: At the end of the article, you will find the table of contents.
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Atopic dermatitis (AD) is a chronic inflammatory disorder of the skin, accompanied by pruritus, eczema, and intense itching. Despite the availability of topical agents, many patients use unregulated topical treatments, which may contribute to the development of resistant skin infections. To study the efficacy and safety of a new rice bran oil-diluted ointment for the treatment of AD. A randomized, open-label, 12-week study enrolled participants with mild-to-moderate AD and used a randomized, single-blinded design for the study, with participants splitting into 4 groups: topical treatment with rice bran oil-diluted ointment, emollient-based ointment (Control), or an emollient cream (vehicle) and none of the aforementioned treatments. The primary outcome was the improvement of subjective symptom scores of AD. Secondary outcomes included the AD Area and Severity Index score, transepidermal water loss, erythema, and scaling of the skin. Safety was evaluated by adverse events, treatment-related skin rashes, and tolerability. Study completion rate was higher in the ointment group (76%) than in the other groups (69-70%). There was
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A 20-year-old male presented with a 3-month history of a lesion in the right breast. The lesion was initially asymptomatic, but it had enlarged over time and was mildly tender. There was no history of trauma or previous medical problems. The patient was a nonsmoker and denied any drug use. Physical examination revealed a soft, nontender, mobile lesion with an indurated ulcerated base involving 10 cm in diameter ([Image 1](#f1-dp0504a16){ref-type=”fig”}).
QUESTIONS
=========
**Question 1:** What is the diagnosis?
**Question 2:** What is the most likely pathophysiologic mechanism?
**Question 3:** When would the diagnosis of *Kaposi*’s sarcoma be ruled out?
**Question 4:** What should one consider in the differential diagnosis?
**Question 5:** When would you suspect primary cutaneous lymphoma or lymphomatoid granulomatosis?
**Question 6:** What should one consider in the differential diagnosis?
**Question 7:** What are the diagnostic criteria for primary cutaneous large B-cell lymphoma?
**Question 8:** What should one consider in the differential diagnosis?
**Question 9:** Which is the likely treatment of primary cutaneous small cleaved cell lymphoma?
**Question 10:** Which is the most likely histological subtype of primary cutaneous follicular lymphoma?
**Question 11:** Which can be used to distinguish primary cutaneous follicular lymphoma from secondary cutaneous follicular lymphoma?
**Question 12:** Which is the likely treatment of primary cutaneous follicular lymphoma?
**Question 13:** Which is the likely treatment of primary cutaneous follicular lymphoma?
**Question 14:** What should one consider
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